secobarbital will reduce the level or effect of etoposide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
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secobarbital will lessen the level or effect of lonafarnib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib is a delicate CYP3A4 substrate. Coadministration with powerful or average CYP3A4 inducers is contraindicated.
secobarbital will lessen the extent or effect of estropipate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
secobarbital will reduce the extent or effect of eletriptan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
secobarbital will lessen the extent or effect of stiripentol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. If not able to avoid coadministration of stiripentol with strong CYP3A4 inducers, maximize stiripentol dose.
This drug is often a member with the barbiturate drug class, like phenobarbital, and is particularly assumed to exert very similar enzyme induction to that of phenobarbital.
If you will not be able to get a complete evening's sleep section for 406 ipc (at least seven hours) immediately after taking the missed dose, skip the skipped dose and go back to your normal time.
Seconal Sodium (secobarbital sodium capsules) might impair the mental and/or physical abilities needed for that general performance of potentially hazardous duties, like driving a car or operating equipment. The individual must be cautioned appropriately.
You have a higher chance for performing these activities should you drink alcohol or just take other medicines which make you sleepy with a SEDATIVE-HYPNOTIC. Described functions include:
Withdrawal symptoms take place in infants born to Ladies who get barbiturates all through the last trimester of pregnancy (see Drug Abuse and Dependence).
Protect the patient's airway and support air flow and perfusion. Meticulously observe and manage, within acceptable restrictions, the affected individual's critical symptoms, blood gases, serum electrolytes, and so on. Absorption of drugs from the gastrointestinal tract could be decreased by offering activated charcoal, which, in many cases, is much more effective than emesis or lavage; consider charcoal rather than or In combination with gastric emptying.
secobarbital and olopatadine intranasal both enhance sedation. Prevent or Use Alternate Drug. Coadministration boosts chance of CNS melancholy, which may result in additive impairment of psychomotor general performance and bring about daytime impairment.